variable penetrance


WELLCOME OPEN RESEARCH LAUNCH INCLUDES DMDD EMBRYO PHENOTYPING PAPER

Today sees the launch of Wellcome Open Research, a new publication platform for Wellcome Trust funded researchers. A set of articles released to coincide with the launch includes ‘Highly variable penetrance of abnormal phenotypes in embryonic lethal knockout mice‘, a publication by the DMDD Programme. It explores the results of systematic efforts by the […]

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3 NEW RESULTS FROM KNOCKOUT MOUSE SCREENS

Around a third of mammalian genes are essential for life, and the recent Nature paper from the IMPC  ‘High-throughput discovery of novel developmental phenotypes‘ [1] describes some achievements from sytematic study of these genes in knockout mice. Screens like those of the IMPC and DMDD are vital to understand gene […]