HREM


HREM WORKSHOP

HREM workshop at the Division of Anatomy, Medical University of Vienna, 23-24 May 2019 HREM was the main imaging method used by the DMDD programme to enable phenotyping of embryos from genetically engineered mouse lines. Workshop tutors will include former members of the DMDD programme who developed and perfected the […]

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JOIN OUR HREM AND PHENOTYPING WORKSHOP

Generation and interpretation of HREM data from normal and mutant E14.5 mouse embryos in the DMDD programme   20 – 22 October 2017 The Medical University of Vienna   Deciphering the Mechanisms of Developmental Disorders (DMDD) is a large-scale imaging and phenotyping programme for genetically modified mouse embryos. For embryos […]


DMDD WEBSITE ENHANCEMENTS

Following user testing of the DMDD website at the BSCB/BSDB meeting earlier this year, we’ve been working behind the scenes on some enhancements to our site. The changes went live today, and here’s a rundown of what’s new. HOMEPAGE Perhaps the first thing you might notice is our updated homepage. […]


Brd2 embryo.

HREM IMAGING REVEALS DETAILS OF ABNORMAL EMBRYO DEVELOPMENT

High Resolution Episcopic Microscopy (HREM) is a technique that allows embryos to be imaged in unprecedented 3D detail. It’s the main imaging method used by the DMDD programme – we use it to identify a wide range of developmental abnormalities that result from mouse gene knockouts. The detail revealed by […]


NEW DMDD YOUTUBE CHANNEL

This week sees the launch of the DMDD YouTube channel. We’ve added videos that explore different aspects of our embryonic-lethal mouse data, providing a new way to visualise phenotypes that we’ve observed in our knockout lines. For example, this video compares HREM data from a Psph mutant embryo with its wild-type […]

Brd2 embryo.

An Adamts3 embryo displays bifid ureter and subcutaneous edema.

DATA RELEASE – AUGUST 2016

New embryonic-lethal knockout mouse lines are now available on the DMDD database. If you haven’t previously taken a look at our data (or even if you have) now would be a good time to explore our website.  We’ve added new embryo phenotype data and HREM images for many knockout lines, […]