Data releases


DATA RELEASE HIGHLIGHTS – JUNE 2018

Following today’s data release, the DMDD website now contains detailed phenotype data for nearly 700 embryos from 82 different knockout mouse lines. Highlights include the identification of limb defects and cysts in Col4a2 knockouts and replication of the major features of Meckel syndrome in B9d2 knockouts. We have begun to […]


9.5 MILLION EMBRYO IMAGES NOW AVAILABLE

A new set of DMDD embryo and placenta data has been released today, taking our total dataset to 9.5 million images of around 1300 embryos. Phenotypes are available for embryos from 73 different knockout lines, and we have phenotyped the placentas from 124 lines. We have also added data on […]

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NEW PHENOTYPE DATA FOR EMBRYOS AND PLACENTAS

Today, DMDD has released many new images and phenotypes for embryos and placentas from embryonic lethal knockout mouse lines. We now hold data on 70 mutant lines that have been phenotyped in detail using the Mammalian Phenotype ontology. The resulting data is freely available to the scientific community and is […]


NEW EMBRYO PHENOTYPE DATA AVAILABLE

New image and phenotype data for embryos and placentas from embryonic lethal knockout mouse lines has been made available on the DMDD website today. The knockout data includes the ciliary gene Rpgrip1l as well as Atg16l1, a gene encoding a protein that forms part of a larger complex needed for […]


A NEW BASELINE RNA EXPRESSION PROFILE FOR MOUSE EMBRYOS

Knowing the ‘normal’ expression of genes during embryo development is key to understanding the differences that occur due to genetic mutations. As part of work to understand the underlying transcriptional processes in developing embryos from knockout mouse lines, DMDD has now released a gene expression profile for wild-type mouse embryos […]


An Adamts3 embryo displays bifid ureter and subcutaneous edema.

DATA RELEASE – AUGUST 2016

New embryonic-lethal knockout mouse lines are now available on the DMDD database. If you haven’t previously taken a look at our data (or even if you have) now would be a good time to explore our website.  We’ve added new embryo phenotype data and HREM images for many knockout lines, […]


DATA RELEASE – MAY 2016

New DMDD data is now available on our website. This week we’ve added HREM embryo image stacks for 12 new lines, embryo phenotype data for 12 lines and placental phenotype data for a further 10 lines. For full details on what we’ve released see the bottom of this post, or […]

Brd2 placentas display reduced vascular density.